Resveratrol for Atherosclerosis: Potential Mechanisms
- 1 Institute for Atherosclerosis Research, Osennyaya Moscow, Russia
- 2 Chazov National Medical Research Center of Cardiology of the Ministry of Health of the Russian Federation, Moscow, Russia
- 3 Institute of Experimental Cardiology, National Medical Research Center of Cardiology, Moscow, Russia
- 4 Institute of General Pathology and Pathophysiology, Laboratory of Angiopathology, Moscow, Russia
Abstract
Cardiovascular disease is a big problem around the world. At the heart of most serious cardiovascular diseases is such a pathology as atherosclerosis. Atherosclerosis is a complex set of interactions between inflammation, oxidative stress, lipid disorders, and other molecular, genetic, and lifestyle factors. It is this complexity and multicomponent nature of atherogenesis that make the treatment of atherosclerosis a non-trivial task. Currently, there are no entirely effective strategies for preventing or treating atherosclerosis. Nevertheless, various medications demonstrate varying degrees of effectiveness in relation to processes linked to atherogenesis. In this review, we reviewed a list of possible mechanisms that may contribute to the effectiveness of resveratrol against atherosclerosis.
DOI: https://doi.org/10.3844/ojbsci.2026.26.02.032
Copyright: © 2026 Anastasia Vladimirovna Poznyak, Sergey Kozlov, Gulalek A Babayeva, Vasily Nikolaevich Sukhorukov, Alexander Nikolaevich Orekhov, Stanislav Anatolievich Antonov, Ulyana Vyacheslavovna Rozhkova and Vsevolod Vyacheslavovich Pavshintsev. This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Resveratrol
- Inflammation
- Atherosclerosis
- Cardiovascular Disease