Determination of Iron Deficiency among Human Immunodeficiency Virus Sero Positives

Abstract

Problem statement: Iron is an important dietary mineral and involves in various body functions. In humans, iron is an essential component of proteins involved in oxygen transport. It is also essential for the regulation of cell growth and differentiation. Iron and its binding protein have immune regulatory properties and shifting of immune regulatory balances by iron excess or deficiency may produce severe, deleterious physiology effects. Human with advance human immunodeficiency virus infection present some evidence of iron accumulation. Ferritin concentration increases with HIV disease progression. Increased iron stores predisposed to certain microbial infections leading to the decreased iron level. This association may cause immune system impair by HIV. Approach: A total of 49 HIV patient serum sample were collected 16 HIV/AIDS male patients and 33 HIV/AIDS female patients. Serum iron concentration was analyzed by Atomic Absorption Spectrophotometer (AAS). Result: Presence study documented the prevalence of iron deficiency among HIV sero positives Conclusion: Proper Iron supplementation provides sufficient iron to restore normal storage levels of iron and to replenish hemoglobin deficits thereby increase the survival of HIV sero positives.