Case Report Open Access

An Unusual Case of Leptospirosis Presenting as Glomerulonephritis With Crescents

Felipe Guedes Bezerra1, Ana Flávia de Holanda Veloso2, Yago Sucupira Amaral1, Thiago de Paula Pessoa Franco Silva2 and Anaiara Lucena Queiroz2
  • 1 Department of Nephrology, Walter Cantídio University Hospital, Ceara Federal University, Brazil
  • 2 Department of Clinical Medicine, Walter Cantídio University Hospital, Ceara Federal University, Brazil

Abstract

Leptospirosis is a zoonosis caused by the spirochete Leptospira, which commonly affects the kidneys. Varied renal findings, most commonly tubulointerstitial nephritis, are found in human kidney biopsies and in vivo models. Remarkably, glomeruli are usually spared in this disease. However, some cases report evidence of glomerular damage. We describe a case of leptospirosis with fibroepithelial crescents, a rare histopathological finding.

American Journal of Infectious Diseases
Volume 22 No. 1, 2026, 1-3

DOI: https://doi.org/10.3844/ajidsp.2026.1.3

Submitted On: 14 May 2024 Published On: 6 August 2026

How to Cite: Bezerra, F. G., Veloso, A. F. H., Amaral, Y. S., Silva, T. P. P. F. & Queiroz, A. L. (2026). An Unusual Case of Leptospirosis Presenting as Glomerulonephritis With Crescents. American Journal of Infectious Diseases, 22(1), 1-3. https://doi.org/10.3844/ajidsp.2026.1.3

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Keywords

  • Leptospirosis
  • Glomerulonephritis
  • Crescentic Glomerulonephritis
  • Fibroepithelial Crescents
  • Acute Kidney Injury (AKI)