Relationship between Outcomes of COVID19, its Susceptibility and Blood Groups

Abstract

COVID-19, a viral infection spread across the world affecting many people around the world. In ABO blood type, certain types are more prone to infections and causes severe symptoms. Relationship between ABO blood type and COVID -19 still needs to be found out. A prospective cohort study was conducted to evaluate a relationship between ABO blood type and COVID-19. Data was collected from 148 patients who presented for COVID testing through PCR or nasal swab tests. COVID positive patient’s blood test was performed to find out ABO blood group/type and their symptoms with which they presented. The blood group distributions, age and gender of these patients were recorded. It was seen that there is a statistically significant association between COVID and blood group A+, A-, B+ with p-value of 0.01, 0.03 and 0.01 respectively and no statistical significance was found between B-, O+, O-, AB+ and AB- with P-value of 0.06, 0.1, 0.9, 0.7 and 0.8 respectively. Multi variate analysis performed showed age, blood group and ICU stay to be significantly associated with COVID with p-value of <0.01, 0.05, <0.01 and gender to be non-significantly associated with COVID with p-value of 0.7. Blood group A+, A- and B+ are more prone to contract COVID virus with more severe symptoms. Fever and cough have been to be positively associated with COVID cases and found to be affecting patient’s health. Age is also found be affecting patient’s life, with a higher chance of contracting COVID-19 as the increases.