Overview of Klebsiella Pneumoniae as a Nosocomial Pathogen and ESBL Producing Strains in Iran

Abstract

Klebsiella pneumoniae is one of the most important human bacterial pathogens with an extensive range of community and hospital acquired infections that may lead to morbidity and mortality. Evaluating the prevalence and epidemic sources of infections and the pathogenicity mechanism of bacteria can be investigated by various typing methods. The emergence of multi-drug resistant strains and extended-spectrum ß-lactamase (ESBL) producing isolates has already become a great challenge in nosocomial infection incidence. There are several reports on ESBL isolates of K. pneumoniae in Iran. However, our aim is a comprehensive analysis on ESBL isolates K. pneumoniae from different parts of Iran which has not yet been performed.